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GSTs are responsible for the first step in acrolein metabolization, consisting in its conjugation with GSH

Plant Physiol 161:519 Mur LAJ, Brown IR, Darby RM, Bestwick CS, Bi YM, Mansfield JW, Draper J (2000) A loss of resistance to avirulent bacterial pathogens in tobacco is associated with the attenuation of a salicylic acid-potentiated oxidative burst

10.3390/nu11010177 99

They work by inhibiting tyrosinase activity, which reduces melanin production, and by shifting melanin production from darker eumelanin to lighter pheomelanin

To that end, the present review provides a novel perspective on the triple role of GSTs (detoxification, regulation of cell signalling and fertilisation), and reports their localisation in sperm, seminal plasma and the male reproductive tract